Press Release: Identifying Youth as “At Risk” for Mental Problems May Be Less Stigmatizing Than Mental Health Symptoms

Study Suggests Benefits of Early Intervention Outweigh Stigma of At-Risk Labeling  

September 29, 2015 — There is an emergent and promising field of research on schizophrenia prevention, yet little is known about the potential harm and risks inherent in identifying and labeling young people at risk. A study led by researchers at Columbia University’s Mailman School of Public Health and New York State Psychiatric Institute found that young people identified as at clinical risk for psychosis described feeling stigmatized by the symptoms that led them to seek help to a relatively stronger degree than the risk label, or the stigma of coming to a specialized clinic. The study is the first to address the separate effects of symptoms and labeling on stigma in young people identified as at clinical high risk for schizophrenia and related psychotic disorders. Findings are online in the journal Schizophrenia Research.

“The clinical high-risk state is an incredibly important advance in psychiatry that enables identification of at-risk youth prior to development of full psychosis,” said Lawrence H. Yang, PhD, associate professor of Epidemiology at the Mailman School of Public Health and first author. “We were able to distinguish feelings of stigma due to attending a specialized high-risk clinic from the stigma of having symptoms and experiences. While the stigma of symptoms and experiences appear greater, the results indicate that both forms of stigma provide targets for intervention.”

Fewer than one in three young people identified as at-risk develop psychosis. The vast majority, therefore, either has residual symptoms or improves entirely. “Because there is the risk of having ‘false positives,’ it is especially important to demonstrate that stigma induced by the ‘at risk’ label appears less than that of symptoms,” said Yang. “But even for the true positives—those one in three that do develop psychosis—it is important to learn that the stigma of symptoms is a relatively stronger contributor to stigma, as such it is precisely the stigma that would be reduced by early intervention.”

The new paper reports the findings from a prospective cohort study at the New York State Psychiatric Institute at Columbia University at the Center of Prevention and Evaluation, or COPE, a comprehensive program that offers treatment and resources to participants about early symptoms and risk of schizophrenia. Upon joining COPE through community identification in clinics and schools, young people were told that while they were at increased risk for psychosis as compared with the general population, it was likely that they would not develop psychosis. They were also told that if they did develop psychosis, they would receive immediate treatment, which tends to be effective. In this study, young people were asked about their stigma experiences on average about 11 months after they entered the COPE program.

Yang is also the principal investigator of a multi-site five-year project currently funded by the National Institutes of Health that is building upon the current study to understand stigma better in the clinical high risk state for psychosis. This project, which is being conducted at New York State Psychiatric Institute, Beth Israel Deaconess-Harvard Medical Center, and Maine Medical Center, will enable Yang to corroborate these initial findings, as well as to examine whether vulnerability to stigma is affected by social cognition, like recognizing others’ intents and emotions in their facial expressions and in what they say.

“Regarding labeling-related stigma, our findings indicate that similar to other psychiatric conditions—awareness of stereotypes was relatively high, and feelings of shame were significant,” noted Yang. “However, the fact that there were also positive emotions associated with identification — such as increased relief and understanding– and with coming to a specialized high-risk clinic indicates the beneficial effects of being identified as clinical high-risk.”

“This study confirms that the young people we identified as at risk for psychosis were more troubled by the symptoms they were having than by any label given to them,” said Cheryl Corcoran, MD, senior author and Columbia University assistant professor of Clinical Psychiatry and a research scientist at the New York State Psychiatric Institute. “We are also encouraged to learn how much these young people resist or disagree with pervasive negative stereotypes of psychosis or schizophrenia and that this relative lack of stigma associated with a risk label might mean that more young people will seek out the treatment and services they need. Our task then is to develop the best treatments we can to reduce the risk of psychosis, and make them widely available to the very teens and young adults who need them.”

The study was supported by the National Institute of Mental Health (grants 1 R01 MH096027-01, K23 MH06627901A2, and R21MH086125); National Center for Advancing Translational Sciences (NIHUL1 TR000040); the New York State Office of Mental Hygiene; the Brain and Behavior Research Foundation Young Investigator Award (17539); the Rollin M. Gerstacker Foundation; and the Calderone Prize. Data were collected using an Irving CaMPR award and the New York State Office of Mental Health provided all of the infrastructure for COPE.

The authors declare that they have no conflicts of interest.

About Columbia University’s Mailman School of Public Health

Founded in 1922, Columbia University’s Mailman School of Public Health pursues an agenda of research, education, and service to address the critical and complex public health issues affecting New Yorkers, the nation and the world. The Mailman School is the third largest recipient of NIH grants among schools of public health. Its over 450 multi-disciplinary faculty members work in more than 100 countries around the world, addressing such issues as preventing infectious and chronic diseases, environmental health, maternal and child health, health policy, climate change & health, and public health preparedness. It is a leader in public health education with over 1,300 graduate students from more than 40 nations pursuing a variety of master’s and doctoral degree programs. The Mailman School is also home to numerous world-renowned research centers including ICAP (formerly the International Center for AIDS Care and Treatment Programs) and the Center for Infection and Immunity. For more information, please visit

Columbia University Department of Psychiatry & New York State Psychiatric Institute

Columbia Psychiatry is ranked among the best departments and psychiatric research facilities in the nation and has contributed greatly to the understanding and treatment of psychiatric disorders. Located at the New York State Psychiatric Institute on the NewYork-Presbyterian Hospital/Columbia University Medical Center campus in Washington Heights, the department enjoys a rich and productive collaborative relationship with physicians in various disciplines at Columbia University’s College of Physician’s and Surgeons. Columbia Psychiatry is home to distinguished clinicians and researchers noted for their clinical and research advances in the diagnosis and treatment of depression, suicide, schizophrenia, bipolar and anxiety disorders, eating disorders, and childhood psychiatric disorders. Visit and for more information.

Contact: Stephanie Berger, Columbia University’s Mailman School of Public Health, 212-305-4372[email protected]

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New Work Shows Marriage Outcomes for those with Psychosis Differ by Urban vs. Rural Settings in China

A new paper from Lawrence Yang entitled “Marriage outcome and relationship with urban versus rural context for individuals with psychosis in a population-based study in China.” was just published in Social Psychiatry and Psychiatric Epidemiology.

The Chinese symbol for marriage

The Chinese symbol for marriage

Social integration for people with psychosis in low and middle income countries remains an important issue that might facilitate or hinder their recovery. However, this issue has rarely been investigated across urban versus rural settings in the same country. Yang’s team therefore examined marriage outcomes for individuals with psychosis in urban vs. rural settings in China in a large community-based study in four provinces representing 12% of China’s population (393 individuals with psychosis). Main results showed that while urban and rural residents had similar impairments due to symptoms, urban female residents were 2.72 times more likely to be unmarried than their rural counterparts. Further stratified analyses indicated that this marital disadvantage occurred primarily among urban females with an earlier age of onset.

The findings indicate that urban contexts impeded opportunities for marriage for female individuals with psychosis specifically. These data suggest that urban women with earlier age of onset have difficulty in obtaining marriage which may be related to economic expectations of women in urban areas. This research is especially significant regarding the rapid urbanization of China and how it might adversely effect social integration opportunities for people with psychosis.

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