Project Renaissance (2008-2013) 
This five year study is funded by the National Institutes of Drug Abuse (NIDA) to examine the efficacy of a couple-based HIV and Overdose prevention intervention in reducing HIV risk behavior and overdoses. The study is being conducted with 400 injecting drug users and their main sexual partners (N=800) in Kazakhstan. The findings will have important HIV prevention implications for drug users and their main sex partners in Kazakhstan and other Central Asian countries.
Primary outcomes:
to reduce incidence of overdose and mortality, incidence of HIV and other STIs, sexual and drug risk behaviors
Why HIV and Naloxone OD prevention Should be Integrated
•Overdose is the leading cause of death among IDUs living with HIV
•HIV infection increases risk of overdose
•Access to naloxone among IDUs found to increase their engagement in HIV and drug services
•Some evidence suggests that IDUs who experience OD are also likely to engage in HIV risks