Below are examples of a few ways to use the Health Sciences Library’s (HSL) Resources to find the answers to these questions.
1. What is the pathophysiology of hemophilia A?
- This is a background or general question which can be answered by consulting a textbook. For information on the pathophysiology (or physiopathology) of hemophilia A, search e-books from Access Medicine. From the HSL homepage http://library.cumc.columbia.edu/ select>Top Resources> Access Medicine; in the search box type Hemophilia A Pathophysiology; the results (for example) include Williams’ Hematology. Scroll to find a chapter on: Classic Hemophilia, Factor VIII Deficiency. A similar search can be conducted in StatRef, which is another e-book resource. From the HSL homepage select >Top Resources>StatRef.
- A search in the MeSH database (within PubMed) for hemophilia a can also be done, select the subheading physiopathology from the list of subheadings. Add the selection to the ‘Add to search builder’ on right of page and then select ‘Search PubMed’. This will launch a search in PubMed, based on your selections.
2. Are there any books that provide an overview on dental care for medically compromised patients?
- A search can be done in CLIO (Columbia’s Library Catalog).
- HSL homepage http://library.cumc.columbia.edu/ select>Top Resources> CLIO
- Do a subject search In CLIO for “Oral manifestations of general diseases,” results include:
- The oral-systemic health connection: a guide to patient care / edited by Michael Glick.
Published Hanover Park, IL: Quintessence Publishing Co, Inc, [2014]
RK61 .O72 2014 - A CLIO subject search: “Dental Care for Chronically Ill” results in titles including:
The ADA practical guide to patients with medical conditions [electronic resource]
Published Chichester, West Sussex : Wiley-Blackwell, 2012.
Online / full text: http://www.columbia.edu/cgi-bin/cul/resolve?clio10231554 - Little and Falace’s dental management of the medically compromised patient
Published St. Louis, Mo. : Elsevier/Mosby, c2013.
Location: Health Sciences Reference (Non-Circ) – RK55.S53 L72 2013
- HSL homepage http://library.cumc.columbia.edu/ select>Top Resources> CLIO
3. What is the recommended management of patients with hemophilia A undergoing oral surgery?
- From the HSL homepage http://library.cumc.columbia.edu/ select>Top Resources> PubMed
- Search strategy suggestion: Hemophilia A AND oral surgery
- Below are a few selected citations
- Antifibrinolytic therapy for preventing oral bleeding in patients with haemophilia or Von Willebrand disease undergoing minor oral surgery or dental extractions. van Galen KP, Engelen ET, Mauser-Bunschoten EP, van Es RJ, Schutgens RE. Cochrane Database Syst Rev. 2015 Dec 24;(12):CD011385. doi: 10.1002/14651858.CD011385.pub2. PMID: 26704192
- Oral surgery-associated postoperative bleeding in haemophilia patients – a tertiary centre’s two decade experience. Givol N, Hirschhorn A, Lubetsky A, Bashari D, Kenet G. Haemophilia. 2015 Mar;21(2):234-40. doi: 10.1111/hae.12573. Epub 2014 Dec 4. PMID: 25470999
- Search strategy suggestion: Hemophilia A AND oral surgery
- Another search option is to only search for Hemophilia A and then limit your retrieval to Dental Journals by selecting the filters on the left pane in your PubMed search; or you may opt to type this in the search box as follows: hemophilia a AND jsubsetd; (Note: jsubsetd stands for Journal Subset Dental; Use this limit with caution, as you will greatly reduce your results).
- Some citations retrieved are as follows:
- Congenital bleeding disorders and dental surgery. Spivakovsky S, Keenan AV, Congiusta M, Spivakovsky Y. Evid Based Dent. 2015 Sep;16(3):90-1. doi: 10.1038/sj.ebd.6401121. No abstract available. PMID: 26492808
- Hemophilia and oral health. Zaliuniene R, Peciuliene V, Brukiene V, Aleksejuniene J. Stomatologija. 2014;16(4):127-31. Review. PMID: 25896036
- Management of dental extraction in patients with Haemophilia A and B: a report of 58 extractions. Peisker A, Raschke GF, Schultze-Mosgau S. Med Oral Patol Oral Cir Bucal. 2014 Jan 1;19(1):e55-60. PMID: 24121912
- Some citations retrieved are as follows:
- A search can also be done in Embase; select Embase from the HSL homepage http://library.cumc.columbia.edu/ select>Top Resources>Embase; Search strategy suggestion: ‘Dental Procedure’/exp AND ‘Hemophilia A’/exp
- Some citations are as follows:
- Combined factor V and VIII deficiency in a young woman with abundant bleeding after tooth extraction. Ates I., Kaplan M., Tokgoz G., Ceran F., Akalin S., Ozet G. Blood Research 2016 51:1 (67-68)
- Factors influencing risk of bleeding after dental extraction in hemophilia patients. Miljić P., Bodroźić J., Elezović I., Juris̈ić M., Brković B., Antić D., Leković D., Mitrovic M. Journal of Thrombosis and Haemostasis 2015 13 SUPPL. 2 (586-587)
- Some citations are as follows:
4. What are the practice guidelines for treating patients with hemophilia?
Search strategy suggestion: PubMed: Hemophilia A [Mesh] AND Practice Guideline [ptyp]Note: [Mesh] refers to Medical Subject Headings; [ptyp] refers to publication type.
- Below are a few selected citations from PubMed.
- Towards standardization of clot waveform analysis and recommendations for its clinical applications. Shima M, Thachil J, Nair SC, Srivastava A; Scientific and Standardization Committee. J Thromb Haemost. 2013 Jul;11(7):1417-20. Review. No abstract available. PMID: 23648068
- Srivastava A, Brewer AK, Mauser-Bunschoten EP, Key NS, Kitchen S, Llinas A, Ludlam CA, Mahlangu JN, Mulder K, Poon MC, Street A; Treatment Guidelines Working Group on Behalf of The World Federation Of Hemophilia. Haemophilia. 2013 Jan;19(1):e1-47. PMID: 22776238
- Recommendations for assessment, monitoring and follow-up of patients with haemophilia. de Moerloose P, Fischer K, Lambert T, Windyga J, Batorova A, Lavigne-Lissalde G, Rocino A, Astermark J, Hermans C. Haemophilia. 2012 May;18(3):319-25. PMID: 21992772
Additional Useful Resources:
- AHRQ National Guideline clearing House https://www.guideline.gov
- ADA Center for Evidence-Based Dentistry http://ebd.ada.org/en
- Evidence-Based Endodontics Literature Database http://www.evidencebasedendo.com/
- Center for Evidence-Based Dentistry http://www.cebd.org/
- CDC Division of Oral Health – Guidelines and Recommendations https://www.cdc.gov/oralhealth/guidelines.htm
- Cochrane Oral Health: http://oralhealth.cochrane.org/
- TRIP Database https://www.tripdatabase.com/
- CATs Library Critically Appraised Topics https://cats.uthscsa.edu/search.php
- Learning at your own pace (Tutorials) from the Health Sciences Library’s homepage http://library.cumc.columbia.edu/learning-your-pace-tutorials
- “A practical approach to evidence-based dentistry: understanding and applying the principles of EDB” Journal of the American Dental Association, November, Volume 145 (11): p.1105-1107; PMID 25359637 http://rd8hp6du2b.search.serialssolutions.com/OpenURL_local?sid=Entrez:PubMed&id=pmid:25359637
Additional Assistance:
- Visit the Health Sciences Library’s Homepage at: http://library.cumc.columbia.edu/ and select links under ‘Ask a Question’ section to:
- Get an email response: http://library.cumc.columbia.edu/ask-question
- Drop in during on-call hours or reserve time with an informationist: http://library.cumc.columbia.edu/informationist-availability
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